LRP1B functions as a receptor for Pseudomonas exotoxin
نویسندگان
چکیده
منابع مشابه
Pseudomonas exotoxin: recombinant conjugates as therapeutic agents.
Pseudomonas exotoxin: structure and function Pseudornonas exotoxin (PE) is a bacterial protein produced by €3. aeruginosa that is toxic for most mammalian cells [for reviews see 1, 21. The mature protein is a proenzyme and, after activation, exhibits both NAD hydrolase activity and ADP-ribosyltransferase activity. When added to mammalian cells the toxin binds to the alpha 2-macroglobulin recept...
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ژورنال
عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
سال: 2005
ISSN: 0925-4439
DOI: 10.1016/j.bbadis.2005.06.007